Boronic acid, (5-bromo-2-ethoxyphenyl)-

Boronic acid, (5-bromo-2-ethoxyphenyl)- - Names and Identifiers

Name	Boronic acid, (5-bromo-2-ethoxyphenyl)-
Synonyms	5-Bromo-2-ethoxyphenyL Boronic acid, (5-bromo-2-ethoxyphenyl)- Boronic acid, B-(5-bromo-2-ethoxyphenyl)- Boronic acid, (5-bromo-2-ethoxyphenyl)- (9CI)
CAS	352525-82-7

Boronic acid, (5-bromo-2-ethoxyphenyl)- - Physico-chemical Properties

Molecular Formula	C8H10BBrO3
Molar Mass	244.88
Density	1.53±0.1 g/cm3(Predicted)
Melting Point	125-129°C(lit.)
Boling Point	385.6±52.0 °C(Predicted)
pKa	7.60±0.58(Predicted)
Storage Condition	2-8℃

Boronic acid, (5-bromo-2-ethoxyphenyl)- - Risk and Safety

WGK Germany

Boronic acid, (5-bromo-2-ethoxyphenyl)- - Introduction

Boronic acid, (5-bromo-2-ethoxyphenyl)-(Boronic acid, (5-bromo-2-ethoxyphenyl)-) is an organic compound whose chemical formula is C8H10BO3Br.

Nature:
Boronic acid, (5-bromo-2-ethoxyphenyl)-is a white crystal or crystalline powder with good stability at room temperature. It is soluble in organic solvents such as ethanol, dimethylformamide (DMF) and dimethylsulfoxide (DMSO), and insoluble in water.

Use:
Boronic acid, (5-bromo-2-ethoxyphenyl)-is an important intermediate in organic synthesis. It can be used to catalyze coupling reactions, such as Suzuki-Miyaura reaction, Negishi reaction and Stille reaction, to synthesize aromatic compounds with important biological activities. In addition, it can also be used to prepare liquid crystal display materials, fluorescent dyes and pesticides.

Preparation Method:
The preparation method of Boronic acid, (5-bromo-2-ethoxyphenyl)-can be achieved by reacting 5-bromo-2-ethoxyphenylmethanol with boric acid. The reaction is generally carried out under basic conditions under an inert atmosphere.

Safety Information:
Boronic acid, (5-bromo-2-ethoxyphenyl)-is relatively stable at room temperature, but should avoid contact with strong oxidants and strong acids. Pay attention to protective measures during operation and wear appropriate protective gloves, goggles and protective clothing. If ingestion or contact with skin or eyes, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-10 22:29:15